Lactobacillus reuteri in the treatment of Helicobacter pylori in Sardinian patients

Open study to investigate if the eradication rate of H. pylori in adults is improved by L. reuteri DSM 17938, as an adjunct during 10-day eradication therapy and for 10 days thereafter. Forty-five (45) patients were included.

The rate of eradication was 93.3% (42/45). In 2/4 (50%) previously treated for H. pylori the infection was also eradicated.

Side effects were reported in 8 subjects: mild diarrhoea for a few days (n=5), and abdominal discomfort (n=3).

Conclusion: Proton pump inhibitor-tetracycline-metronidazole-L. reuteri therapy provided high eradication rates with few side effects, and excellent compliance.

BioGaia Gastrus

BioGaia Gastrus is a food supplement containing the patented lactic acid bacterium Lactobacillus reuteri Gastrus®/TM (L. reuteri DSM 17938 and L. reuteri ATCC PTA 6475). Because both strains in L. reuteri Gastrus naturally colonize humans they have a strong adaptation to persist and interact with humans.

Can Protectis tablets be used by patients that suffer from intolerance and/or allergy?

Biogaia Protectis tablets can be used by patients suffering from milk protein allergy and / or are sensitive to lactose / gluten.

  • A probiotic bacteria can be grown on different types of media
  • The L. reuteri Protectis culture used in BioGaia Protectis tablets are grown either on skim milk or a barley based media.
  • After production the bacteria are diluted in the product
  • Analytical data reveals milk protein, lactose and gluten in the culture. However, in the finished product neither milk protein nor lactose are detectable, and the gluten level is below EU limit value for gluten-free products.

Is Lactobacillus reuteri growing in the product?

No, the bacteria are in a dormant state and become activated and fully metabolically active when they come in contact with the saliva. This happens quickly, by the time they reach the stomach, they can start to colonize.

Should BioGaia probiotic products be taken with or without food?

The conditions under which Lactobacillus reuteri is taken are not critical. Hypothetically, the elevated pH shortly after the intake of food might have a positive impact on the survival of Lactobacillus reuteri, but it is more important that Lactobacillus reuteri is taken on a regular daily basis and at a time of the day that is suitable for the consumer.

Do I need to take Lactobacillus reuteri every day?

Yes, since the intestinal levels are depleted within about a week after discontinuing use. The resident microbiota of an individual is relatively fixed and thereby highly resistant to the establishment of “newcomers”. Even an indigenous bacterium like Lactobacillus reuteri should be taken on a regular basis, since most people of modern society does not get colonized by Lactobacillus reuteri during infancy. By taking BioGaia probiotics regularly you maintain the total daily supply of lactobacilli.