Reduction in breath methane and relief of constipation

 

Background: Detection of the gas methane (CH4) in exhaled breath is positively correlated to constipation, according to some research. Intestinal CH4 can slow intestinal transit time, and directly inhibit gut motility. Whether these alterations are a cause or a consequence of constipation is unknown.

This is an open trial, investigating the effect of L. reuteri Protectis DSM 17938 on the frequency of bowel movements and the level of methane in exhaled breath. The subjects were 20 constipated adults, all presenting with methane in their breath. Lactulose breath test was used at baseline and after 4 weeks of consumption of L. reuteri Protectis (2 tablets per day)

Positive detection of CH4 was defined as: production of > 5 ppm of CH4 at any time during four hours after oral ingestion of a 200-ml solution with 10 g of lactulose (= lactulose breath test).

 

 

Conclusion: Methane production in constipated adults can be reduced by daily ingestion of L. reuteri Protectis for four weeks. Reduced production of methane was associated with normalized number of weekly bowel movements. Ingestion of L. reuteri Protectis seems to modify the composition or the metabolism of methane producers of the gut microbiota.

BioGaia Protectis D3

BioGaia Protectis D3 is a food supplement containing the patented lactic acid bacterium Lactobacillus reuteri Protectis®/TM (L. reuteri DSM 17938) that helps the good microorganisms restore a natural balance in the gut. Because L. reuteri Protectis naturally colonizes humans it has a strong adaptation to persist and interact with humans.

BioGaia Life Top Straw

BioGaia Probiotic straw contain Lactobacillus reuteri Protectis, a natural lactobacillus that helps the good microorganisms restore a natural balance in the gut. L. reuteri Protectis naturally colonizes humans it has a strong adaptation to persist and interact with humans.

BioGaia Protectis

BioGaia Protectis is a food supplement containing the patented lactic acid bacterium Lactobacillus reuteri Protectis®/TM (L. reuteri DSM 17938) that helps the good microorganisms restore a natural balance in the gut. Because L. reuteri Protectis naturally colonizes humans it has a strong adaptation to persist and interact with humans.

Can Protectis tablets be used by patients that suffer from intolerance and/or allergy?

Biogaia Protectis tablets can be used by patients suffering from milk protein allergy and / or are sensitive to lactose / gluten.

  • A probiotic bacteria can be grown on different types of media
  • The L. reuteri Protectis culture used in BioGaia Protectis tablets are grown either on skim milk or a barley based media.
  • After production the bacteria are diluted in the product
  • Analytical data reveals milk protein, lactose and gluten in the culture. However, in the finished product neither milk protein nor lactose are detectable, and the gluten level is below EU limit value for gluten-free products.

What is Lactobacillus reuteri Protectis?

Lactobacillus reuteri Protectis is a strain of the species Lactobacillus reuteri that has been tested in more than 122 clinical trials (in humans). It is used in products such as drops and tablets. Its scientific designation is Lactobacillus reuteri DSM 17938.

Is Lactobacillus reuteri growing in the product?

No, the bacteria are in a dormant state and become activated and fully metabolically active when they come in contact with the saliva. This happens quickly, by the time they reach the stomach, they can start to colonize.