Airways allergic inflammation and L. reuterii treatments in asthmatic children

Randomized, double-blind and placebo controlled trial of the effect of L. reuteri in children 6-14y with well-controlled asthma, on airway inflammation measured by certain inflammatory parameters, and clinically. L. reuteri or placebo was ingested during 60 days, with 22 in the active group and21 in the placebo group.

Compared to placebo L. reuteri significantly reduced airway inflammation, shown as changed levels in exhaled breath condensate:

• reduction of exhaled nitric oxide (FeNO)

• reduction of the cytokine IL-2

• increase of the cytokine IL-10


Bronchial airway inflammation was significantly reduced, without change in clinical parameters.



Miraglia del Giudice M, Maiello N, Decimo F, Fusco N, D’Agostino B, Sullo N, Capasso M, Salpietro V, Gitto E, Ciprandi G, Marseglia GL, Perrone L. Airways allergic inflammation and L. reuterii treatments in asthmatic children. J Biol Regul Homeost Agents. 2012;26(1, Suppl.):35(S)-40(S).

Crawling baby

For the avoidance of doubt, BioGaia’s products are food supplements, and the information on this part of the website should not be interpreted as our products are intended to diagnose, treat, cure or prevent any disease.

The information on this part of the website is intended only for health care and business professionals. If you are not a health care or business professional and would like to learn more about the indications BioGaia works with, please visit our Expertise pages.

Please read terms & conditions before accepting. By clicking on the button “I acknowledge and accept” you confirm that you are a healthcare or business professional and have read and understood this disclaimer including the terms and conditions.