Colonization of the human gastrointestinal tract by Lactobacillus reuteri

This was an open study with the objective to study the colonisation of the colon by Lactobacillus reuteri ATCC 55730, in ten adult patients undergoing a colonoscopy examination.

Lactobacillus reuteri was ingested at a dosage of 10^9 CFU/day, as yoghurt (5 patients) or as probiotic fruit juice (5 patients) for 12 days before the colonoscopy. Faecal samples were analysed before and after 12 days of consumption of the probiotic foods. Biopsies from all three parts of the colon were sampled on day 12. Identification methods for Lactobacillus reuteri were based on biochemical properties and a gene-based method (RiboPrint system). No subject was colonised with Lactobacillus reuteri before the start of the study.

Live Lactobacillus reuteri cells were found on day 12 in faecal samples from 3/5 subjects in the yoghurt group and in all five in the juice group. Lactobacillus reuteri was identified at the strain level in the colon biopsies from one subject.

Conclusion: The daily consumption of Lactobacillus reuteri in yoghurt or fruit juice for 12 days resulted in successful colonisation of 80% of the study subjects, measured as live bacteria cells in faecal samples. One of the subjects also had the administered Lactobacillus reuteri strain cultivated from the colon biopsies.



Björkman P. Colonisation of the human gastrointestinal tract by the lactic acid bacterium Lactobacillus reuteri. M.Sc. thesis, Dept. of Food Technology, University of Helsinki, Finland. 1999;15

Crawling baby

For the avoidance of doubt, BioGaia’s products are food supplements, and the information on this part of the website should not be interpreted as our products are intended to diagnose, treat, cure or prevent any disease.

The information on this part of the website is intended only for health care and business professionals. If you are not a health care or business professional and would like to learn more about the indications BioGaia works with, please visit our Expertise pages.

Please read terms & conditions before accepting. By clicking on the button “I acknowledge and accept” you confirm that you are a healthcare or business professional and have read and understood this disclaimer including the terms and conditions.