A study in several parts beginning with the effect of different probiotics on the growth of Streptococcus mutans (a bacterium correlated with the risk of caries).

A laboratory screening of probiotic bacteria isolated from 18 different fermented dairy products available in Japan showed that Lactobacillus reuteri ATCC 55730 was the only strain that inhibited the growth of Streptococcus mutans. A further laboratory study verified that Lactobacillus reuteri had no harmful effect on dental enamel. A clinical study was also performed in which 40 subjects with healthy mouths took part. Half of them ingested 95 g daily of yoghurt containing Lactobacillus reuteri with their lunch, while half ingested the same quantity of a placebo yoghurt. After 2 weeks the groups changed the study product and the subjects thus served as their own controls.

Both groups showed a significant decrease in the number of Streptococcus mutans in the saliva during the 2-week period when ingesting Lactobacillus reuteri. The group which started with Lactobacillus reuteri yoghurt, also had a significantly inhibiting effect on Streptococcus mutans in the two subsequent weeks when ingesting the placebo yoghurt.


Conclusion: The daily ingestion of yoghurt containing Lactobacillus reuteri for a period of two weeks significantly reduced the number of Streptococcus mutans in the saliva of healthy subjects. This effect was consistent also for at least two weeks after ending the intake of the probiotic yoghurt. Lactobacillus reuteri was the only bacterium in a laboratory screening test of probiotic bacteria from 18 fermented milk products that showed inhibition of Streptococcus mutans.



Nikawa H, Makihira S, Fukushima H, Nishimura H, Ozaki Y, Ishida K, Darmawan S, Hamada T, Hara K, Matsumoto A, Takemoto T, Objectivei R. Lactobacillus reuteri in fermented bovine milk decreases the oral carriage of mutans streptococci. Int J Food Microbiol 2004;95:219-223.

Crawling baby

For the avoidance of doubt, BioGaia’s products are food supplements, and the information on this part of the website should not be interpreted as our products are intended to diagnose, treat, cure or prevent any disease.

The information on this part of the website is intended only for health care and business professionals. If you are not a health care or business professional and would like to learn more about the indications BioGaia works with, please visit our Expertise pages.

Please read terms & conditions before accepting. By clicking on the button “I acknowledge and accept” you confirm that you are a healthcare or business professional and have read and understood this disclaimer including the terms and conditions.