One of the most studied probiotics in the world

BioGaia’s probiotic products with Lactibacillus reuteri are among the most scientifically well-documented probiotics in the world with regard to both efficacy and safety. To date the efficacy and safety of BioGaia’s different strains of L. reuteri have been documented in 203 clinical studies in 17,200 people of all ages.

Lactobacillus reuteri has shown result in 105 clinical studies in children, from newborns up to 18 years old, and 98 studies in adults. Probiotic strains that have been used in clinical trials are BioGaia Protectis (DSM 17938), BioGaia Gastrus (ATCC PTA 6475) and BioGaia Prodentis (ATCC PTA 52899. Results have been published in 180 papers in scientific journals (February 2019).


Research on bacteria

Research on bacteria and their significance for our health has exploded in the past decade and is now one of the hottest research areas. At BioGaia, research on Lactobacillus reuteri has been taking place for almost 30 years. A unique network of specialists at around 50 research institutes and clinics studies not only the effectiveness of Lactobacillus reuteri for various indications but also how and why it works. Read more about our Research network.

Clinical trials supporting the use of BioGaia Probiotics

Lactobacillus reuteri Protectis, Prodentis, and Gastrus

203 completed clinical trials in 17,200 individuals

140 randomised, double-blind / blind, placebo-controlled studies in 11,700 subjects

63 open studies in 5,500 subjects

67 studies in 0-3y in 8,200 subjects


Clinical studies

To date, 203 clinical studies using BioGaia’s human strains of Lactobacillus reuteri have been performed on 17,500 individuals of all ages. Results have been published in 180 articles in scientific journals (February 2019). Read more


What is Lactobacillus reuteri?

Research has shown that Lactobacillus reuteri is a species of bacteria that has developed a mutualistic relationship with its specific host over millions of years. Read more


Our health areas

The human microbiota, i.e. microorganisms residing in the gastrointestinal tract, is believed to be established directly from birth and during the early years of life. Read more