One of the most studied probiotics in the world

BioGaia’s probiotic products with Lactibacillus reuteri are among the most scientifically well-documented probiotics in the world with regard to both efficacy and safety. To date the efficacy and safety of BioGaia’s different strains of L. reuteri have been documented in 203 clinical studies in 17,200 people of all ages.

Lactobacillus reuteri has shown result in 105 clinical studies in children, from newborns up to 18 years old, and 98 studies in adults. Probiotic strains that have been used in clinical trials are BioGaia Protectis (DSM 17938), BioGaia Gastrus (ATCC PTA 6475) and BioGaia Prodentis (ATCC PTA 52899. Results have been published in 180 papers in scientific journals (February 2019).

The results indicate that L. reuteri Protectis may help in functional gastrointestinal disorders such as colic, regurgitation, constipation and functional abdominal pain. Different L. reuteri strains have also been used in clinical trials for indications like acute gastroenteritis and antibiotic associated side-effects. Oral health and infection protection are other areas where L. reuteri strains have been shown beneficial.

 

Clinical trials supporting the use of BioGaia Probiotics

Lactobacillus reuteri Protectis, Prodentis, and Gastrus

203 completed clinical trials in 17,200 individuals

140 randomised, double-blind / blind, placebo-controlled studies in 11,700 subjects

63 open studies in 5,500 subjects

67 studies in 0-3y in 8,200 subjects

 

Clinical studies

To date, 202 clinical studies using BioGaia’s human strains of Lactobacillus reuteri have been performed on 17,500 individuals of all ages. Results have been published in 180 articles in scientific journals (February 2019). Read more

 

What is Lactobacillus reuteri?

Research has shown that Lactobacillus reuteri is a species of bacteria that has developed a mutualistic relationship with its specific host over millions of years. Read more

 

Baby and child health

The human microbiota, i.e. microorganisms residing in the gastrointestinal tract, is believed to be established directly from birth and during the early years of life. Read more

 

Gut health

The balance between good and bad bacteria are believed to be exceptionally important for human health. In a balanced gut, good bacteria outnumber bad ones by ten to one. If bad bacteria start to exceed it may lead to various health conditions such as constipation or diarrhea. Read more

 

Oral health

There are more than 700 bacterial species that protect the mouth against bacteria that form plaque and cause gum problems. When the balance among oral bacteria is disrupted due to inadequate oral hygiene, stress and poor diet can plaque forming bacteria gain the upper hand, causing gum problems. Read more

 

Research network

BioGaia collaborates with specialists at around 50 research institutes and clinics in a unique global research network. Many of these researchers are among the foremost in their areas. Read more