Since every gastrointestinal tract is unique some individuals might experience a temporary change in gut motility. BioGaia probiotics very rarely cause side effects in the amounts recommended for the products. Some individuals might experience gas (flatulence), but that generally disappears after a few days. No serious adverse effects have been observed in clinical trials up to the maximum tested dosage of 10 billion CFU per day.
Lactobacillus reuteri (L. reuteri) is a probiotic bacteria that has co-evolved with humans since the beginning of time, and because of that it is adapted to its host. L. reuteri is among the first bacterial species to naturally become established in the microbiota of the newborn. BioGaia probiotic products with L. reuteri are among the most scientifically well-documented probiotics in the world with regard to both efficacy and safety. To date 202 clinical studies with BioGaia’s L. reuteri-strains have been performed in more than 17,200 people of all ages. Positive results have been shown for several gastrointestinal disorders and oral health. Results have been published in 180 articles in scientific journals (February 2019).
Read more about Lactobacillus reuteri.
Lactobacillus reuteri Protectis is a probiotic strain that has been tested in more than 148 human clinical studies (February 2019). Products containing this strain are for example BioGaia Protectis baby drops and BioGaia Protectis tabs. The scientific designation of Lactobacillus reuteri Protectis is L. reuteri DSM 17938.
The name BioGaia is made up of two words, Bio and Gaia. Bio stands for life and living organisms, natural, and ecological systems. Gaia, according to Greek mythology, is a goddess, the creator of all life, the sister of Eros and a personification of the Earth.
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The bacteria are alive but in a dormant state. They become activated and fully metabolically active when they come in contact with the saliva. By the time they reach the stomach they can start to colonize.
Based on the results of clinical studies, the dose level of 100 million CFU/day has been chosen as a safe and efficient dose for Lactobacillus reuteri Protectis. The corresponding dose for Lactobacillus reuteri Prodentis and Gastrus is 200 million CFU/day.
The culture, which is used in the product, is fermented either on a skim milk or a barley based medium. Analytical data reveals milk protein, lactose and gluten in the culture. However, in the finished product neither milk protein nor lactose are detectable, and the gluten level is below EU limit value for Gluten free products according to Commission Implementing Regulation (EU) No 828/2014 (<20 mg/kg). As allergen food labelling regulation may vary from country to country, local regulation has always to beconsidered when labelling this product.
It is difficult to give an exact answer as the composition of each gut microbiota is unique. Depending on indication/symtom clinical studies have shown different results.* If you are a healthcare professional please read more about our clinical studies here.
*Due to the regulatory situation we cannot communicate the effect of our products or claim health benefits to consumers. In Europe the use of nutrition and health claims is regulated by the European Food Safety Authority (EFSA) and today there are no approved health claims for probiotics.
The spots are not dangerous and the product can still be used. BioGaia Protectis tablets contains ascorbic acid, which is an antioxidant that contributes to the stability of the tablets. Over time the ascorbic acid oxidizes and the color becomes darker. This darkening is seen as small “spots” on the tablet.
In BioGaia we are constantly working on improving our products. The Easydropper is a new delivery system for probiotic products. It has an improved drop function which facilitates the administration of the product and less environmental impact compared to glass bottles.
Yes, BioGaia producs can be taken together with antibiotics. Antibiotics disrupt the natural balance in the gut. As BioGaia products help to maintain a balanced gut microbiota, they may reduce common side effects of antibiotics. We recommend to take the antibiotic two hours before or after the probiotic.
It cannot be recommended to use BioGaia’s probiotic Lactobacillus reuteri strains for yoghurt production. The BioGaia L. reuteri strains are probiotic bacteria of human origin that thrives in the human GI tract and exerts its effect there. It does not produce the right compounds that turn milk into yoghurt. They do not multiply properly and do not give texture or flavor to the product when fermented in any type of food.
BioGaia cannot take responsibility for the safety of “yoghurt products” produced at home with our probiotic strains.
It does not matter if BioGaia’s probiotic products are taken with or without food. What is important is to take it on a daily basis.
The recommended daily dose of Lactobacillus reuteri Protectis is 100 million CFU (Colony Forming Units). This dose is provided by 5 drops of BioGaia Protectis drops or 1 BioGaia Protectis tablet.
Yes, for more than one reason. The resident microbiota of an individual is relatively fixed and thereby highly resistant to the establishment of “newcomers”. Even if L. reuteri is of human and naturally belongs in our bodies, the L. reuteri Protectis strain doesn’t colonize forever, especially not, when given after the age of three.
Even an indigenous bacterium like Lactobacillus reuteri should be taken on a regular basis, since most people of modern society does not get colonized by L. reuteri during infancy. The epithelial lining covers our gastrointestinal tract and works like a skin on the inside of our bodies. The main task of our ”inner skin” is to differentiate between what should be absorbed and what should not be let into our bodies. Biopsies have shown that Lactobacillus reuteri is temporarily binding to our epithelial lining. However, since the cells in our epithelial lining is replaced every fourth day, the majority of L. reuteri cells are also washed away within a week or so. Since L. reuteri colonization is transient, every day intake is recommended to ensure adequate and stable levels of L. reuteri in the gastrointestinal tract.
Read more about the epithelial lining – Gatekeepers in the gut
Yes, it is safe to take BioGaia products together with pharmaceuticals and other supplements.*
*If you have any medical conditions, always consult your healthcare professional for advice.
The recommended dose of a probiotic does not depend on bodyweight. BioGaia’s clinical studies show efficacy with the same dose both in children and adults.
Clinical studies have shown that BioGaia Protectis drops are safe to give from day of birth.
Yes, the drops can be added to formula and/or breast milk. Do not add to liquids warmer than 37°C/99°F. If adding to liquids, make sure to consume within the same day.
- We strongly recommend giving our probiotic drops by spoon.
- Shake well for 10 seconds before each use to mix the bacteria culture with the oil.
- To dispense the drops tilt the bottle and give by spoon.
- Use 5 drops once daily.
- Do not add to hot drink or food as this may damage the live bacteria.
The recommended daily dose of Lactobacillus reuteri Prodentis is 200 million CFU, or 2 x 10^8 CFU. You get this dose by consuming 1 BioGaia Prodentis lozenge or 5 drops of BioGaia Prodentis drops.
In BioGaia Prodentis lozenges neither milk protein nor lactose are detectable, and the gluten level is below EU limit value for gluten-free products. As food regulation varies from country to country, the product labelling may differ.
In BioGaia Protectis tablets neither milk protein nor lactose are detectable, and the gluten level is below EU limit value for gluten-free products. As food regulation varies from country to country, the product labelling may differ.
BioGaia Protectis drops do not contain lactose or milk protein. In the finished product the gluten level is below EU limit value for gluten-free products. As food regulation varies from country to country, the product labelling may differ.
All BioGaia products are free from common allergens such as egg, peanuts, tree nuts, fish, shellfish and soy.
Our products are sold by distribution partners in around 100 countries. Usually, they are sold through the major pharmacy chains. For information on where to buy our products, please contact our distribution partner in your country.
Probiotics are good bacteria that can be found in dietary supplements and sometimes in dairy products. Probiotics are defined as ”live microorganisms that, when administered in adequate amounts, confer a health benefit on the host.” (WHO/FAO 2002, Hill C et al. 2014). An important criterium for qualifying as a true probiotic is that health benefits have been proven in clinical studies. Furthermore, a probiotic product must contain the same bacterial strain(s) and the same dose that was used in the clinical studies.
Probiotics have shown beneficial effects in gastrointestinal disorders such as colic, constipation, and diarrhea. Promising results have also been shown for the maintenance of a normal immune function and protection against infections. Further, probiotics have shown benefits in oral health. BioGaia offers clinically-proven and user-friendly probiotic products to consumers world wide. Due to the regulatory situation we cannot communicate the effect of our products or claim health benefits. In Europe the use of nutrition and health claims is regulated by the European Food Safety Authority (EFSA) and today there are no approved health claims for probiotics.
Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. Prebiotics are fibres and carbohydrates that stimulate the growth of bacteria in the gastrointestinal tract.
Bacteria are classified into genus, species and strains. Probiotic strains of the same species have different characteristics, and may therefore have different health effects. For example, clinical studies with the two strains, Lactobacillus reuteri ATCC PTA 6475 and Lactobacillus reuteri DSM 17938, have shown different effects in clinical studies. That is why a probiotic product must be defined on strain level.
Multi-strain products containing several strains in high doses do not necessarily have a better effect than a single-strain product. Important criteria when choosing a probiotic product are:
• The probiotic bacteria must be defined on strain level
• The probiotic product must have been tested in human clinical studies, with the same dose and with the same bacterial strain(s) as in the commercial product.
Exposure to high temperatures and/or high humidity will significantly shorten the shelf-life of the product. However, the product will still be safe to use.
BioGaia Protectis drops comes in two different versions, we therefore recommend you to follow the instructions on the package. However, if room temperature is above 25°C/77°F we always recommend storage in the fridge.
BioGaia Protectis bady drops should not be stored in the freezer, as this will significantly shorten the shelf-life of the product.
BioGaia products comes in different versions, we therefore recommend you to follow the instructions on the package. However, if room temperature is above 25°C/77°F we always recommend storage in the fridge.